BDBM50564598 CHEMBL4784194

SMILES CC(C)(O)c1cc(Nc2cc(Oc3cn(nc3-c3ccc4OCOc4c3)C3CC3)ccn2)ccn1

InChI Key InChIKey=VGZJHPJPSRIDQI-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50564598   

TargetTGF-beta receptor type-1(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50564598(CHEMBL4784194)
Affinity DataIC50: 22nMAssay Description:Inhibition of ALK5 (unknown origin) measured after 120 mins of incubation by ADP-Glo kinase assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/29/2022
Entry Details Article
PubMed
TargetTGF-beta receptor type-1(Mouse)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50564598(CHEMBL4784194)
Affinity DataIC50: 92nMAssay Description:Inhibition of TGF-beta type 1 receptor in mouse NIH3T3 cells expressing Luc-Smad 2/3 measured after 24 hrs incubation by cell based Bright-Glo Lucife...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/29/2022
Entry Details Article
PubMed