BDBM50564532 CHEMBL4794457

SMILES COc1cc(\C=N\NC(=O)Nc2ccc(cc2)-c2c(sc(N3CCOCC3)c2C#N)-c2nc[nH]n2)cc(OC)c1OC

InChI Key InChIKey=RLIKUWUEQIRQLU-UHFFFAOYSA-N

Data  1 IC50

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50564532   

TargetPhosphatidylinositol 3-kinase regulatory subunit alpha/4,5-bisphosphate 3-kinase catalytic subunit alpha isoform(Human)
Guizhou Medical University

Curated by ChEMBL

LigandBDBM50564532(CHEMBL4794457)Copy SMILESCopy InChI

Affinity DataIC50: 110nMAssay Description:Inhibition of His-tagged human full length PI3Kalpha coexpressed with p85 alpha in baculovirus expression system using PIP2 peptide as substrate incu...More data for this Ligand-Target Pair

Target InfoPDB
UniProtKB/SwissProt
GoogleScholar

Ligand InfoPC cidPC sidSimilars

In Depth
Date in BDB:
3/29/2022
Entry Details Article
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