BDBM50564363 CHEMBL4791998

SMILES Fc1ccc2NC(=O)C(=C3/Nc4ccccc4/C/3=NOCCN3CCNCC3)c2c1

InChI Key InChIKey=WMWHVTDZNIVNIE-UHFFFAOYSA-N

Data  10 IC50  1 Kd

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 11 hits for monomerid = 50564363   

TargetReceptor-type tyrosine-protein kinase FLT3(Human)
Gwangju Institute of Science and Technology

Curated by ChEMBL
LigandPNGBDBM50564363(CHEMBL4791998)
Affinity DataIC50: 0.870nMAssay Description:Inhibition of recombinant His-tagged human FLT3 expressed in baculovirus expression system using peptide substrate incubated for 30 mins in presence ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/29/2022
Entry Details Article
PubMed
TargetReceptor-type tyrosine-protein kinase FLT3(Human)
Gwangju Institute of Science and Technology

Curated by ChEMBL
LigandPNGBDBM50564363(CHEMBL4791998)
Affinity DataIC50: 0.320nMAssay Description:Inhibition of human FLT3 D835Y mutant in presence of ATPMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/29/2022
Entry Details Article
PubMed
TargetVascular endothelial growth factor receptor 3(Human)
Gwangju Institute of Science and Technology

Curated by ChEMBL
LigandPNGBDBM50564363(CHEMBL4791998)
Affinity DataIC50: 24nMAssay Description:Inhibition of human FLT4 in presence of ATPMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/29/2022
Entry Details Article
PubMed
TargetProto-oncogene tyrosine-protein kinase Src(Human)
Gwangju Institute of Science and Technology

Curated by ChEMBL
LigandPNGBDBM50564363(CHEMBL4791998)
Affinity DataIC50: 9.5nMAssay Description:Inhibition of human c-SRC in presence of ATPMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/29/2022
Entry Details Article
PubMed
TargetMacrophage colony-stimulating factor 1 receptor(Human)
Gwangju Institute of Science and Technology

Curated by ChEMBL
LigandPNGBDBM50564363(CHEMBL4791998)
Affinity DataIC50: 4.20nMAssay Description:Inhibition of human FMS in presence of ATPMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/29/2022
Entry Details Article
PubMed
TargetTyrosine-protein kinase Mer(Human)
Gwangju Institute of Science and Technology

Curated by ChEMBL
LigandPNGBDBM50564363(CHEMBL4791998)
Affinity DataIC50: 3nMAssay Description:Inhibition of human MER in presence of ATPMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/29/2022
Entry Details Article
PubMed
TargetProto-oncogene tyrosine-protein kinase receptor Ret(Human)
Gwangju Institute of Science and Technology

Curated by ChEMBL
LigandPNGBDBM50564363(CHEMBL4791998)
Affinity DataIC50: 1.20nMAssay Description:Inhibition of human RET in presence of ATPMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/29/2022
Entry Details Article
PubMed
TargetHigh affinity nerve growth factor receptor(Human)
Gwangju Institute of Science and Technology

Curated by ChEMBL
LigandPNGBDBM50564363(CHEMBL4791998)
Affinity DataIC50: 6.90nMAssay Description:Inhibition of human TrkA in presence of ATPMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/29/2022
Entry Details Article
PubMed
TargetBDNF/NT-3 growth factors receptor(Human)
Gwangju Institute of Science and Technology

Curated by ChEMBL
LigandPNGBDBM50564363(CHEMBL4791998)
Affinity DataIC50: 2nMAssay Description:Inhibition of human TrkB in presence of ATPMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/29/2022
Entry Details Article
PubMed
TargetReceptor-type tyrosine-protein kinase FLT3(Human)
Gwangju Institute of Science and Technology

Curated by ChEMBL
LigandPNGBDBM50564363(CHEMBL4791998)
Affinity DataKd: <0.25nMAssay Description:Binding affinity to human FLT3 ITD mutant in presence of ATP by Lanthascreen Eu kinase binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/29/2022
Entry Details Article
PubMed
TargetMaternal embryonic leucine zipper kinase(Human)
Gwangju Institute of Science and Technology

Curated by ChEMBL
LigandPNGBDBM50564363(CHEMBL4791998)
Affinity DataIC50: 5.5nMAssay Description:Inhibition of human MELK in presence of ATPMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/29/2022
Entry Details Article
PubMed