BDBM50564348 CHEMBL4780410

SMILES FC(F)(F)c1cc(NC(=O)NC2CCN(CC2)c2ncnc3[nH]ncc23)cc(c1)C(F)(F)F

InChI Key InChIKey=KGUGNCJQOQZVJW-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50564348   

TargetSerine/threonine-protein kinase PAK 1(Human)
Sichuan University

Curated by ChEMBL
LigandPNGBDBM50564348(CHEMBL4780410)
Affinity DataIC50: 170nMAssay Description:Inhibition of PAK1 (unknown origin) using lipid substrate measured after 40 mins by ADP-glo kinase assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/29/2022
Entry Details Article
PubMed
TargetSerine/threonine-protein kinase PAK 2(Human)
Sichuan University

Curated by ChEMBL
LigandPNGBDBM50564348(CHEMBL4780410)
Affinity DataIC50: 1.04E+3nMAssay Description:Inhibition of PAK2 (unknown origin) using lipid substrate measured after 40 mins by ADP-glo kinase assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/29/2022
Entry Details Article
PubMed
TargetSerine/threonine-protein kinase PAK 3(Human)
Sichuan University

Curated by ChEMBL
LigandPNGBDBM50564348(CHEMBL4780410)
Affinity DataIC50: 1.37E+3nMAssay Description:Inhibition of PAK3 (unknown origin) using lipid substrate measured after 40 mins by ADP-glo kinase assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/29/2022
Entry Details Article
PubMed