BDBM50564263 CHEMBL4788954

SMILES COc1ccc(cc1)-c1ccc2c(NC(=O)CCCCCCC(=O)NO)n[nH]c2c1

InChI Key InChIKey=OQKZYTUPMGUCDP-UHFFFAOYSA-N

Data  6 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50564263   

TargetHistone deacetylase 1(Human)
Jiangsu Key Laboratory For Functional Substance of Chinese Medicine

Curated by ChEMBL
LigandPNGBDBM50564263(CHEMBL4788954)
Affinity DataIC50: 2.70nMAssay Description:Inhibition of recombinant human C-terminal His/FLAG-tagged HDAC1 (1 to end residues) expressed in sf9 insect cells using Boc-Lys(Ac)-AMC as substrate...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/29/2022
Entry Details Article
PubMed
TargetHistone deacetylase 2(Human)
Jiangsu Key Laboratory For Functional Substance of Chinese Medicine

Curated by ChEMBL
LigandPNGBDBM50564263(CHEMBL4788954)
Affinity DataIC50: 4.20nMAssay Description:Inhibition of recombinant human C-terminal His-tagged HDAC2 (1 to end residues) expressed in sf9 insect cells using Boc-Lys(Ac)-AMC as substrate incu...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/29/2022
Entry Details Article
PubMed
TargetHistone deacetylase 8(Human)
Jiangsu Key Laboratory For Functional Substance of Chinese Medicine

Curated by ChEMBL
LigandPNGBDBM50564263(CHEMBL4788954)
Affinity DataIC50: 3.60nMAssay Description:Inhibition of recombinant human full length C-terminal His-tagged HDAC8 expressed in sf9 insect cells using Boc-Lys(TFA)-AM as substrate incubated fo...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/29/2022
Entry Details Article
PubMed
TargetHistone deacetylase 1(Human)
Jiangsu Key Laboratory For Functional Substance of Chinese Medicine

Curated by ChEMBL
LigandPNGBDBM50564263(CHEMBL4788954)
Affinity DataIC50: 2.70nMAssay Description:Inhibition of HDAC1 in human HeLa nuclear extract using Boc-Lys(Ac)-AMC as substrateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/21/2023
Entry Details
PubMed
TargetHistone deacetylase 2(Human)
Jiangsu Key Laboratory For Functional Substance of Chinese Medicine

Curated by ChEMBL
LigandPNGBDBM50564263(CHEMBL4788954)
Affinity DataIC50: 4.20nMAssay Description:Inhibition of HDAC2 in human HeLa nuclear extract using Boc-Lys(Ac)-AMC as substrateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/21/2023
Entry Details
PubMed
TargetHistone deacetylase 8(Human)
Jiangsu Key Laboratory For Functional Substance of Chinese Medicine

Curated by ChEMBL
LigandPNGBDBM50564263(CHEMBL4788954)
Affinity DataIC50: 3.60nMAssay Description:Inhibition of HDAC8 in human HeLa nuclear extract using Boc-Lys(Ac)-AMC as substrateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/21/2023
Entry Details
PubMed