BDBM50564145 CHEMBL4778495

SMILES CCc1ccc(CCC2CCc3nc(N)nc(N)c3N2C(=O)CCl)cc1

InChI Key InChIKey=BADSIGKKKLHTOX-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50564145   

TargetMethionine synthase(Human)
Peking University

Curated by ChEMBL
LigandPNGBDBM50564145(CHEMBL4778495)
Affinity DataIC50: 1.21E+4nMAssay Description:Inhibition of human Cobalamin-dependent methionine synthase isolated from HL-60 cells using methyltetrahydrofolate as substrate incubated for 10 mins...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/29/2022
Entry Details Article
PubMed
TargetMethionine synthase(Human)
Peking University

Curated by ChEMBL
LigandPNGBDBM50564145(CHEMBL4778495)
Affinity DataIC50: 4.46E+3nMAssay Description:Inhibition of human Cobalamin-dependent methionine synthase isolated from HL-60 cells using 63 uM of methyltetrahydrofolate as substrate incubated fo...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/29/2022
Entry Details Article
PubMed
TargetMethionine synthase(Human)
Peking University

Curated by ChEMBL
LigandPNGBDBM50564145(CHEMBL4778495)
Affinity DataIC50: 7.64E+3nMAssay Description:Inhibition of human Cobalamin-dependent methionine synthase isolated from HL-60 cells using 126 uM of methyltetrahydrofolate as substrate incubated f...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/29/2022
Entry Details Article
PubMed
TargetMethionine synthase(Human)
Peking University

Curated by ChEMBL
LigandPNGBDBM50564145(CHEMBL4778495)
Affinity DataIC50: 1.21E+4nMAssay Description:Inhibition of human Cobalamin-dependent methionine synthase isolated from HL-60 cells using 252 uM of methyltetrahydrofolate as substrate incubated f...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/29/2022
Entry Details Article
PubMed