BDBM50563964 CHEMBL4791634

SMILES C[C@H]1COCCN1c1ccc2nc(-c3ccc4onc(C)c4c3)n(CC3CCCCC3)c2c1

InChI Key InChIKey=JYCNBHVRGVCHIQ-UHFFFAOYSA-N

Data  1 IC50  1 Kd

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50563964   

TargetBromodomain-containing protein 4(Human)
Guangzhou Medical University

Curated by ChEMBL
LigandPNGBDBM50563964(CHEMBL4791634)
Affinity DataIC50: 180nMAssay Description:Inhibition of HYSGRGK(Ac)GGK(Ac)GLGK(Ac)GGAK(Ac)RHRK(Biotin)-OH binding to recombinant human His6-tagged BRD4 bromodomain 1 (N44 to E168 residues) ex...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/29/2022
Entry Details Article
PubMed
TargetBromodomain-containing protein 4(Human)
Guangzhou Medical University

Curated by ChEMBL
LigandPNGBDBM50563964(CHEMBL4791634)
Affinity DataKd:  81nMAssay Description:Binding affinity to human recombinant His6-tagged BRD4 bromodomain 1 (N44 to E168 residues) expressed in Escherichia coli BL21 (DE3) cells assessed a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/29/2022
Entry Details Article
PubMed