BDBM50563742 CHEMBL4795284

SMILES CCCCCn1ccnc1N

InChI Key InChIKey=BZGNBEDZZHYWHI-UHFFFAOYSA-N

Data  2 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50563742   

TargetToll-like receptor 8(Human)
University of Kansas

Curated by ChEMBL
LigandPNGBDBM50563742(CHEMBL4795284)
Affinity DataEC50:  2.84E+4nMAssay Description:Agonist activity at human TLR8 stably expressed in HEK293 cells cotransfected with secreted alkaline phosphatase assessed as induction of NFkappaB ac...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/29/2022
Entry Details Article
PubMed
TargetToll-like receptor 8(Human)
University of Kansas

Curated by ChEMBL
LigandPNGBDBM50563742(CHEMBL4795284)
Affinity DataEC50:  2.84E+4nMAssay Description:Agonist activity at human TLR8 (27 to 827 residues) stably expressed in human HEK-Blue hTLR8 cells assessed as activation of NFkappaB by SAP reporter...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/19/2024
Entry Details
PubMed