BDBM50563733 CHEMBL4758698

SMILES Cc1c2NCCOc2ncc1-c1cc2\C(=C\c3ccc([nH]3)C3CC3)C(=O)Nc2c(F)c1

InChI Key InChIKey=FFWIIJDLELGDJL-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50563733   

TargetMitogen-activated protein kinase kinase kinase kinase 1(Human)
Smith, Gambrell & Russell

Curated by ChEMBL
LigandPNGBDBM50563733(CHEMBL4758698)
Affinity DataIC50: 0.0500nMAssay Description:Inhibition of recombinant human HPK1 expressed in baculovirus infected insect cells using SRKS1 peptide as substrate incubated for 15 mins followed b...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/29/2022
Entry Details Article
PubMed