BDBM50563355 CHEMBL4800519

SMILES ONC(=O)[C@H]1C[C@@H](CN1S(=O)(=O)c1ccc(cc1)[N+]([O-])=O)NS(=O)(=O)c1ccc(cc1)-c1ccccc1

InChI Key InChIKey=YOSFZMCQPIHTKQ-UHFFFAOYSA-N

Data  6 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50563355   

TargetCarbonic anhydrase 9(Human)
University of Florence

Curated by ChEMBL
LigandPNGBDBM50563355(CHEMBL4800519)
Affinity DataKi:  2.33E+4nMAssay Description:Inhibition of human CA9 incubated for 15 mins by stopped-flow CO2 hydration kinetic assay based Cheng-Prusoff equation analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/29/2022
Entry Details Article
PubMed
TargetCarbonic anhydrase 2(Human)
University of Florence

Curated by ChEMBL
LigandPNGBDBM50563355(CHEMBL4800519)
Affinity DataKi:  4.48E+4nMAssay Description:Inhibition of human CA2 incubated for 15 mins by stopped-flow CO2 hydration kinetic assay based Cheng-Prusoff equation analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/29/2022
Entry Details Article
PubMed
TargetCarbonic anhydrase 1(Human)
University of Florence

Curated by ChEMBL
LigandPNGBDBM50563355(CHEMBL4800519)
Affinity DataKi:  5.29E+4nMAssay Description:Inhibition of human CA1 incubated for 15 mins by stopped-flow CO2 hydration kinetic assay based Cheng-Prusoff equation analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/29/2022
Entry Details Article
PubMed
Target72 kDa type IV collagenase(Human)
University of Florence

Curated by ChEMBL
LigandPNGBDBM50563355(CHEMBL4800519)
Affinity DataKi: >1.00E+5nMAssay Description:Inhibition of MMP2 (unknown origin) using Mca-Lys-Pro-Leu-Gly-Leu-Dpa-Ala-Arg-NH2 as substrate incubated for 5 min followed by substrate addition and...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/29/2022
Entry Details Article
PubMed
TargetMatrix metalloproteinase-9(Human)
University of Florence

Curated by ChEMBL
LigandPNGBDBM50563355(CHEMBL4800519)
Affinity DataKi: >1.00E+5nMAssay Description:Inhibition of MMP9 (unknown origin) using Mca-Lys-Pro-Leu-Gly-Leu-Dpa-Ala-Arg-NH2 as substrate incubated for 5 min followed by substrate addition and...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/29/2022
Entry Details Article
PubMed
TargetCarbonic anhydrase 12(Human)
University of Florence

Curated by ChEMBL
LigandPNGBDBM50563355(CHEMBL4800519)
Affinity DataKi: >1.00E+5nMAssay Description:Inhibition of human CA12 incubated for 15 mins by stopped-flow CO2 hydration kinetic assay based Cheng-Prusoff equation analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/29/2022
Entry Details Article
PubMed