BDBM50563328 CHEMBL4746555

SMILES OC(Cn1ccnc1)(P([O-])([O-])=O)P([O-])([O-])=O

InChI Key InChIKey=XRASPMIURGNCCH-UHFFFAOYSA-J

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50563328   

TargetGeranylgeranyl pyrophosphate synthase(Human)
University of Paris Nord

Curated by ChEMBL
LigandPNGBDBM50563328(CHEMBL4746555)
Affinity DataIC50: 9.10E+3nMAssay Description:Inhibition of GGPPS in human MIA PaCa-2 cells assessed as reduction in cell growth incubated for 72 hrs by MTT assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/29/2022
Entry Details Article
PubMed
TargetGeranylgeranyl pyrophosphate synthase(Human)
University of Paris Nord

Curated by ChEMBL
LigandPNGBDBM50563328(CHEMBL4746555)
Affinity DataIC50: 1.01E+4nMAssay Description:Inhibition of GGPPS in human MDA-MB-231 cells assessed as reduction in cell growth incubated for 72 hrs by MTT assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/29/2022
Entry Details Article
PubMed
TargetGeranylgeranyl pyrophosphate synthase(Human)
University of Paris Nord

Curated by ChEMBL
LigandPNGBDBM50563328(CHEMBL4746555)
Affinity DataIC50: 8.80E+3nMAssay Description:Inhibition of GGPPS in human A549 cells assessed as reduction in cell growth incubated for 72 hrs by MTT assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/29/2022
Entry Details Article
PubMed