BDBM50562892 CHEMBL4759112

SMILES CN(C)C\C=C\C(=O)Nc1cc2ncnc(Nc3ccc(F)c(Cl)c3)c2cc1O[C@@H]1CCOC1

InChI Key InChIKey=WRUDTZAASVCWAT-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50562892   

TargetReceptor tyrosine-protein kinase erbB-2(Human)
Tsinghua University

Curated by ChEMBL
LigandPNGBDBM50562892(CHEMBL4759112)
Affinity DataIC50: 6.20nMAssay Description:Inhibition of HER2 (unknown origin) by mobility shift assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/29/2022
Entry Details Article
PubMed
TargetEpidermal growth factor receptor(Human)
Tsinghua University

Curated by ChEMBL
LigandPNGBDBM50562892(CHEMBL4759112)
Affinity DataIC50: 3nMAssay Description:Inhibition of EGFR L858R/T790M (unknown origin) by mobility shift assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/29/2022
Entry Details Article
PubMed
TargetEpidermal growth factor receptor(Human)
Tsinghua University

Curated by ChEMBL
LigandPNGBDBM50562892(CHEMBL4759112)
Affinity DataIC50: 0.320nMAssay Description:Inhibition of EGFR (unknown origin) by mobility shift assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/29/2022
Entry Details Article
PubMed
TargetEpidermal growth factor receptor(Human)
Tsinghua University

Curated by ChEMBL
LigandPNGBDBM50562892(CHEMBL4759112)
Affinity DataIC50: 0.880nMAssay Description:Inhibition of EGFR L858R (unknown origin) by mobility shift assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/29/2022
Entry Details Article
PubMed