BDBM50562890 CHEMBL4794670

SMILES ONC(=O)CCCn1cc(COc2cc3ncnc(Nc4ccc(OCc5cccc(F)c5)c(Cl)c4)c3cc2NC(=O)C=C)nn1

InChI Key InChIKey=RXCJZPBISMXQDN-UHFFFAOYSA-N

Data  6 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50562890   

TargetHistone deacetylase 2(Human)
Tsinghua University

Curated by ChEMBL
LigandPNGBDBM50562890(CHEMBL4794670)
Affinity DataIC50: 96nMAssay Description:Inhibition of HDAC6 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/29/2022
Entry Details Article
PubMed
TargetReceptor tyrosine-protein kinase erbB-2(Human)
Tsinghua University

Curated by ChEMBL
LigandPNGBDBM50562890(CHEMBL4794670)
Affinity DataIC50: 3.70nMAssay Description:Inhibition of HER2 (unknown origin) by mobility shift assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/29/2022
Entry Details Article
PubMed
TargetHistone deacetylase 1(Human)
Tsinghua University

Curated by ChEMBL
LigandPNGBDBM50562890(CHEMBL4794670)
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of HDAC1 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/29/2022
Entry Details Article
PubMed
TargetEpidermal growth factor receptor(Human)
Tsinghua University

Curated by ChEMBL
LigandPNGBDBM50562890(CHEMBL4794670)
Affinity DataIC50: 15nMAssay Description:Inhibition of EGFR L858R/T790M (unknown origin) by mobility shift assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/29/2022
Entry Details Article
PubMed
TargetEpidermal growth factor receptor(Human)
Tsinghua University

Curated by ChEMBL
LigandPNGBDBM50562890(CHEMBL4794670)
Affinity DataIC50: 1.80nMAssay Description:Inhibition of EGFR (unknown origin) by mobility shift assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/29/2022
Entry Details Article
PubMed
TargetEpidermal growth factor receptor(Human)
Tsinghua University

Curated by ChEMBL
LigandPNGBDBM50562890(CHEMBL4794670)
Affinity DataIC50: 2.90nMAssay Description:Inhibition of EGFR L858R (unknown origin) by mobility shift assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/29/2022
Entry Details Article
PubMed