BDBM50562871 CHEMBL4755763

SMILES O\N=C(/Nc1ccc(F)c(Br)c1)c1nonc1NCCNC(=O)CNc1ccc([N+]([O-])=O)c2nonc12

InChI Key InChIKey=AUGMWJGUUATTKE-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50562871   

TargetIndoleamine 2,3-dioxygenase 1(Human)
Second Military Medical University

Curated by ChEMBL
LigandPNGBDBM50562871(CHEMBL4755763)
Affinity DataIC50: 1.32E+3nMAssay Description:Inhibition of recombinant human IDO1 expressed in Escherichia coli BL21 (DE3) using tryptophan as substrateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/29/2022
Entry Details Article
PubMed
TargetIndoleamine 2,3-dioxygenase 1(Human)
Second Military Medical University

Curated by ChEMBL
LigandPNGBDBM50562871(CHEMBL4755763)
Affinity DataIC50: 5.00E+3nMAssay Description:Inhibition of IDO1 in IFNgamma-stimulated human HeLa cells using tryptophan as substrate measured after 48 hrsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/29/2022
Entry Details Article
PubMed