BDBM50562769 CHEMBL4740785

SMILES CCCN(CCCCNC(=O)c1ccc(cc1)-c1ccc(OCc2cn(CCOCCOCCOCCOCCOCCn3cc(COc4ccc(cc4)-c4ccc(cc4)C(=O)NCCCCN(CCC)C4Cc5ccccc5C4)nn3)nn2)cc1)C1Cc2ccccc2C1

InChI Key InChIKey=VLBMGXWHOLLSJU-UHFFFAOYSA-N

Data  1 KI  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50562769   

TargetD(2) dopamine receptor(Human)
Changzhou University

Curated by ChEMBL
LigandPNGBDBM50562769(CHEMBL4740785)
Affinity DataKi:  59nMAssay Description:Displacement of [3H]raclopride from human D2R isoform 2 stably expressed in HEK293 cell membranes measured after 1 hr by liquid scintillation countin...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/29/2022
Entry Details Article
PubMed
TargetD(2) dopamine receptor(Human)
Changzhou University

Curated by ChEMBL
LigandPNGBDBM50562769(CHEMBL4740785)
Affinity DataEC50:  65nMAssay Description:Agonist activity at human D2R isoform 2 stably expressed in HEK293 cells assessed as inhibition of forskolin-induced increase of cAMP accumulation pr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/29/2022
Entry Details Article
PubMed