BDBM50562750 CHEMBL4742804

SMILES CC(C)c1nc2c(nccc2n1S(=O)(=O)c1cccc(Cl)c1)N1CCNCC1

InChI Key InChIKey=QWMKBPOOVMOXIR-UHFFFAOYSA-N

Data  5 KI  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50562750   

Target5-hydroxytryptamine receptor 6(Human)
Palack£

Curated by ChEMBL
LigandPNGBDBM50562750(CHEMBL4742804)
Affinity DataKi:  3nMAssay Description:Displacement of [3H]-LSD from human 5HT6R expressed in HEK293 cell membranes incubated for 1 hr by micro-beta plate reader based analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/29/2022
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 6(Human)
Palack£

Curated by ChEMBL
LigandPNGBDBM50562750(CHEMBL4742804)
Affinity DataIC50: 5.20nMAssay Description:Neutral antagonist activity at 5HT6R (unknown origin) expressed in 1321N1 cells co-expressing CAMYEL assessed as inhibition of WAY181187-induced cAMP...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/29/2022
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 1A(Human)
Palack£

Curated by ChEMBL
LigandPNGBDBM50562750(CHEMBL4742804)
Affinity DataKi:  239nMAssay Description:Displacement of [3H]-8-OH-DPAT from human 5HT2A expressed in HEK293 cell membranes incubated for 1 hr by micro-beta plate reader based analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/29/2022
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 1A(Human)
Palack£

Curated by ChEMBL
LigandPNGBDBM50562750(CHEMBL4742804)
Affinity DataKi:  307nMAssay Description:Displacement of [3H]-8-OH-DPAT from human 5HT1A expressed in HEK293 cell membranes incubated for 1 hr by micro-beta plate reader based analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/29/2022
Entry Details Article
PubMed
TargetD(2) dopamine receptor(Human)
Palack£

Curated by ChEMBL
LigandPNGBDBM50562750(CHEMBL4742804)
Affinity DataKi:  1.33E+3nMAssay Description:Displacement of [3H]-raclopride from human D2L expressed in CHO-K1 cell membranes incubated for 1 hr by micro-beta plate reader based analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/29/2022
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 7(Human)
Palack£

Curated by ChEMBL
LigandPNGBDBM50562750(CHEMBL4742804)
Affinity DataKi:  3.90E+3nMAssay Description:Displacement of [3H]-5-CT from human 5HT7b expressed in HEK293 cell membranes incubated for 1 hr by micro-beta plate reader based analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/29/2022
Entry Details Article
PubMed