BDBM50562672 CHEMBL4797840

SMILES CNC(=O)c1cc(ccn1)-n1ccc2cc(NC(=O)Nc3ccc(N4CCN(C)CC4)c(c3)C(F)(F)F)ccc12

InChI Key InChIKey=WLUGPPFXRHPACW-UHFFFAOYSA-N

Data  5 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50562672   

TargetVascular endothelial growth factor receptor 3(Human)
University of Sharjah

Curated by ChEMBL
LigandPNGBDBM50562672(CHEMBL4797840)
Affinity DataIC50: 96nMAssay Description:Inhibition of Flt4 (unknown origin) in presence of [gamma33]-ATP by liquid scintillation counting analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/29/2022
Entry Details Article
PubMed
TargetVascular endothelial growth factor receptor 2(Human)
University of Sharjah

Curated by ChEMBL
LigandPNGBDBM50562672(CHEMBL4797840)
Affinity DataIC50: 173nMAssay Description:Inhibition of KDR (unknown origin) in presence of [gamma33]-ATP by liquid scintillation counting analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/29/2022
Entry Details Article
PubMed
TargetMast/stem cell growth factor receptor Kit(Human)
University of Sharjah

Curated by ChEMBL
LigandPNGBDBM50562672(CHEMBL4797840)
Affinity DataIC50: 5.00E+3nMAssay Description:Inhibition of CKIT (unknown origin) in presence of [gamma33]-ATP by liquid scintillation counting analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/29/2022
Entry Details Article
PubMed
TargetPlatelet-derived growth factor receptor alpha(Human)
University of Sharjah

Curated by ChEMBL
LigandPNGBDBM50562672(CHEMBL4797840)
Affinity DataIC50: 5.00E+3nMAssay Description:Inhibition of PDGFRalpha (unknown origin) in presence of [gamma33]-ATP by liquid scintillation counting analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/29/2022
Entry Details Article
PubMed
TargetPotassium voltage-gated channel subfamily H member 2(Human)
University of Sharjah

Curated by ChEMBL
LigandPNGBDBM50562672(CHEMBL4797840)
Affinity DataIC50: 9.00E+7nMAssay Description:Inhibition of human ERG incubated for 3 hrs by competitive fluorescence tracer binding based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/29/2022
Entry Details Article
PubMed