BDBM50562657 CHEMBL4800543

SMILES Nc1ccc(cc1)-c1cc(Nc2ccccc2)c2c(c1)c1ccccc1[nH]c2=O

InChI Key InChIKey=UUCCKGFVSHUDQR-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50562657   

Target72 kDa type IV collagenase(Human)
Universidad Complutense

Curated by ChEMBL
LigandPNGBDBM50562657(CHEMBL4800543)
Affinity DataIC50: 3.20E+4nMAssay Description:Inhibition of recombinant human MMP2 (110 to 452 residues) using Mca-Pro-Leu-Gly-Leu-Dpa-Ala-Arg-NH2 expressed in yeast expression system as substrat...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/29/2022
Entry Details Article
PubMed
TargetNeutrophil collagenase(Human)
Universidad Complutense

Curated by ChEMBL
LigandPNGBDBM50562657(CHEMBL4800543)
Affinity DataIC50: 4.70E+4nMAssay Description:Inhibition of recombinant human MMP8 (99 to 269 residues) using Mca-Pro-Leu-Gly-Leu-Dpa-Ala-Arg-NH2 expressed in Escherichia coli expression system a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/29/2022
Entry Details Article
PubMed
TargetMatrix metalloproteinase-9(Human)
Universidad Complutense

Curated by ChEMBL
LigandPNGBDBM50562657(CHEMBL4800543)
Affinity DataIC50: 2.80E+4nMAssay Description:Inhibition of recombinant human MMP9 (107 to 449 residues) using Mca-Pro-Leu-Gly-Leu-Dpa-Ala-Arg-NH2 expressed in Escherichia coli expression system ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/29/2022
Entry Details Article
PubMed
TargetCollagenase 3(Human)
Universidad Complutense

Curated by ChEMBL
LigandPNGBDBM50562657(CHEMBL4800543)
Affinity DataIC50: 7.30E+4nMAssay Description:Inhibition of recombinant human MMP13 (104 to 274 residues) using Mca-Pro-Leu-Gly-Leu-Dpa-Ala-Arg-NH2 expressed in Escherichia coli expression system...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/29/2022
Entry Details Article
PubMed