BDBM50562651 CHEMBL4788250

SMILES Oc1cccc(CNCCc2c[nH]c3cc(F)ccc23)c1

InChI Key InChIKey=CENJSKAOFDSWLX-UHFFFAOYSA-N

Data  2 KI  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50562651   

Target5-hydroxytryptamine receptor 6(Human)
Normandie Univ

Curated by ChEMBL
LigandPNGBDBM50562651(CHEMBL4788250)
Affinity DataIC50: 2.00E+3nMAssay Description:Antagonist activity at human 5HT6 receptor expressed in COS-7 cells assessed as inhibition of 5HT-induced cAMP accumulation preincubated for 7 mins f...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/29/2022
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 6(Human)
Normandie Univ

Curated by ChEMBL
LigandPNGBDBM50562651(CHEMBL4788250)
Affinity DataKi:  4.30nMAssay Description:Displacement of [3H]-LSD from human 5HT6 receptor expressed in HEK293 cell membrane measured after 60 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/29/2022
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 6(Human)
Normandie Univ

Curated by ChEMBL
LigandPNGBDBM50562651(CHEMBL4788250)
Affinity DataKi:  11nMAssay Description:Displacement of [3H]-LSD from human 5HT6 receptor expressed in HEK293 cell membrane measured after 60 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/29/2022
Entry Details Article
PubMed