BDBM50562649 CHEMBL4761383

SMILES NC(=O)c1cccc2cc(oc12)C(=O)N1CCN(CC1)c1nc(nc(n1)-c1cnc(NC(=O)CN2CCOCC2)cc1C(F)(F)F)N1CCOCC1

InChI Key InChIKey=DFAIABHDMOLQDA-UHFFFAOYSA-N

Data  7 IC50

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 7 hits for monomerid = 50562649   

TargetPoly [ADP-ribose] polymerase 1(Human)
China Pharmaceutical University

Curated by ChEMBL

LigandBDBM50562649(CHEMBL4761383)Copy SMILESCopy InChI

Affinity DataIC50: 14nMAssay Description:Inhibition of PARP1 (unknown origin)More data for this Ligand-Target Pair

Target InfoPDB
UniProtKB/SwissProtUniProtKB/TrEMBL
GoogleScholar

Ligand InfoPC cidPC sidSimilars

In Depth
Date in BDB:
3/29/2022
Entry Details Article
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TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform(Human)
China Pharmaceutical University

Curated by ChEMBL

LigandBDBM50562649(CHEMBL4761383)Copy SMILESCopy InChI

Affinity DataIC50: 64nMAssay Description:Inhibition of PI3Kalpha (unknown origin)More data for this Ligand-Target Pair

Target InfoPDBKEGG
UniProtKB/SwissProt
GoogleScholar

Ligand InfoPC cidPC sidSimilars

In Depth
Date in BDB:
3/29/2022
Entry Details Article
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TargetPotassium voltage-gated channel subfamily H member 2(Human)
China Pharmaceutical University

Curated by ChEMBL

LigandBDBM50562649(CHEMBL4761383)Copy SMILESCopy InChI

Affinity DataIC50: 2.94E+4nMAssay Description:Inhibition of human ERGMore data for this Ligand-Target Pair

Target InfoPDBKEGG
UniProtKB/SwissProtUniProtKB/TrEMBL
GoogleScholar

Ligand InfoPC cidPC sidSimilars

In Depth
Date in BDB:
3/29/2022
Entry Details Article
Copy Entry DOIPubMed
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TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform(Human)
China Pharmaceutical University

Curated by ChEMBL

LigandBDBM50562649(CHEMBL4761383)Copy SMILESCopy InChI

Affinity DataIC50: 1.10E+3nMAssay Description:Inhibition of PI3Kgamma (unknown origin)More data for this Ligand-Target Pair

Target InfoPDBKEGG
UniProtKB/SwissProt
GoogleScholar

Ligand InfoPC cidPC sidSimilars

In Depth
Date in BDB:
3/29/2022
Entry Details Article
Copy Entry DOIPubMed
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TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform(Human)
China Pharmaceutical University

Curated by ChEMBL

LigandBDBM50562649(CHEMBL4761383)Copy SMILESCopy InChI

Affinity DataIC50: 197nMAssay Description:Inhibition of PI3Kdelta (unknown origin)More data for this Ligand-Target Pair

Target InfoPDBKEGG
UniProtKB/SwissProt
GoogleScholar

Ligand InfoPC cidPC sidSimilars

In Depth
Date in BDB:
3/29/2022
Entry Details Article
Copy Entry DOIPubMed
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TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit beta isoform(Human)
China Pharmaceutical University

Curated by ChEMBL

LigandBDBM50562649(CHEMBL4761383)Copy SMILESCopy InChI

Affinity DataIC50: 376nMAssay Description:Inhibition of PI3Kbeta (unknown origin)More data for this Ligand-Target Pair

Target InfoPDBKEGG
UniProtKB/SwissProt
GoogleScholar

Ligand InfoPC cidPC sidSimilars

In Depth
Date in BDB:
3/29/2022
Entry Details Article
Copy Entry DOIPubMed
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TargetPoly [ADP-ribose] polymerase 2(Human)
China Pharmaceutical University

Curated by ChEMBL

LigandBDBM50562649(CHEMBL4761383)Copy SMILESCopy InChI

Affinity DataIC50: 6.20nMAssay Description:Inhibition of PARP2 (unknown origin)More data for this Ligand-Target Pair

Target InfoPDBKEGG
UniProtKB/SwissProt
GoogleScholar

Ligand InfoPC cidPC sidSimilars

In Depth
Date in BDB:
3/29/2022
Entry Details Article
Copy Entry DOIPubMed
Copy Rxn URL