BDBM50562611 CHEMBL4753773

SMILES Cc1ncsc1-c1ccc(CNC(=O)[C@@H]2C[C@@H](O)CN2C(=O)[C@@H](NC(=O)COc2ccc(OCCNC(=O)CCc3ccc(c(C)n3)-c3cnc(NCc4c5CCOc5ccc4F)n4cnnc34)cc2)C(C)(C)C)cc1

InChI Key InChIKey=FSFJUWLIBSALJI-UHFFFAOYSA-N

Data  2 Kd

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50562611   

TargetPolycomb protein EED(Human)
Northwestern University

Curated by ChEMBL
LigandPNGBDBM50562611(CHEMBL4753773)
Affinity DataKd: <1nMAssay Description:Binding affinity to human N-terminal His6-tagged/thrombin cleavage site fused/ AVI-tagged EED (1 to 441 residues) expressed in Escherichia coli BL21(...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/29/2022
Entry Details Article
PubMed
TargetPolycomb protein EED(Human)
Northwestern University

Curated by ChEMBL
LigandPNGBDBM50562611(CHEMBL4753773)
Affinity DataKd:  1nMAssay Description:Binding affinity to EED (unknown origin) assessed as dissociation constantMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/22/2023
Entry Details
PubMed