BDBM50562450 CHEMBL4757974

SMILES COc1cc(Cc2cnc(N)nc2N)cc(OC)c1OCCNc1ccc(cc1)C(=O)NC(Cc1cc2ccccc2[nH]1)C(O)=O

InChI Key InChIKey=UPCNVSHFDYCDFM-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50562450   

TargetDihydrofolate reductase(Human)
Comsats University Islamabad

Curated by ChEMBL
LigandPNGBDBM50562450(CHEMBL4757974)
Affinity DataIC50: 30nMAssay Description:Inhibition of recombinant human DHFR measured by spectrophotometric methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/29/2022
Entry Details Article
PubMed