BDBM50562169 CHEMBL4761277

SMILES COc1ccc(NC(=O)N2CCC(CC2)OCc2c(onc2-c2ccccc2OC(F)(F)F)C2CC2)cc1

InChI Key InChIKey=NPWXJSRCBGCPFQ-UHFFFAOYSA-N

Data  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50562169   

TargetBile acid receptor(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50562169(CHEMBL4761277)
Affinity DataEC50: >1.00E+4nMAssay Description:Agonist activity at human FXR expressed in HEK293T cells co-transfected with BSEP plasmid assessed as receptor transactivation after 24 hrs by BSEP-l...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/28/2022
Entry Details Article
PubMed