BDBM50562062 CHEMBL4754186

SMILES O=c1ccoc2ccc(OCCCN3CCCCCC3)cc12

InChI Key InChIKey=OSWCICCXKIXGDJ-UHFFFAOYSA-N

Data  4 KI  6 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 10 hits for monomerid = 50562062   

TargetAcetylcholinesterase(Human)
Helmholtz-Zentrum Dresden-Rossendor

Curated by ChEMBL
LigandPNGBDBM50562062(CHEMBL4754186)
Affinity DataIC50: 1.06E+4nMAssay Description:Inhibition of human AChEMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/28/2022
Entry Details Article
PubMed
TargetCholinesterase(Human)
Helmholtz-Zentrum Dresden-Rossendor

Curated by ChEMBL
LigandPNGBDBM50562062(CHEMBL4754186)
Affinity DataIC50: 2.50E+4nMAssay Description:Inhibition of human BuChEMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/28/2022
Entry Details Article
PubMed
TargetAcetylcholinesterase(Human)
Helmholtz-Zentrum Dresden-Rossendor

Curated by ChEMBL
LigandPNGBDBM50562062(CHEMBL4754186)
Affinity DataIC50: 1.06E+4nMAssay Description:Inhibition of AChE (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/19/2023
Entry Details
PubMed
TargetCholinesterase(Human)
Helmholtz-Zentrum Dresden-Rossendor

Curated by ChEMBL
LigandPNGBDBM50562062(CHEMBL4754186)
Affinity DataIC50: 2.50E+4nMAssay Description:Inhibition of BChE (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/19/2023
Entry Details
PubMed
TargetAcetylcholinesterase(Human)
Helmholtz-Zentrum Dresden-Rossendor

Curated by ChEMBL
LigandPNGBDBM50562062(CHEMBL4754186)
Affinity DataIC50: 1.06E+4nMAssay Description:Inhibition of human AChEMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/18/2024
Entry Details
PubMed
TargetCholinesterase(Human)
Helmholtz-Zentrum Dresden-Rossendor

Curated by ChEMBL
LigandPNGBDBM50562062(CHEMBL4754186)
Affinity DataIC50: 2.50E+4nMAssay Description:Inhibition of human BuChEMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/18/2024
Entry Details
PubMed
TargetSigma non-opioid intracellular receptor 1(Human)
Helmholtz-Zentrum Dresden-Rossendor

Curated by ChEMBL
LigandPNGBDBM50562062(CHEMBL4754186)
Affinity DataKi:  27nMAssay Description:Displacement of [3H]pentazocine from human sigma 1 receptor expressed in HEK293 cell membrane incubated for 2 hrs by liquid scintillation counting me...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/28/2022
Entry Details Article
PubMed
TargetSigma non-opioid intracellular receptor 1(Human)
Helmholtz-Zentrum Dresden-Rossendor

Curated by ChEMBL
LigandPNGBDBM50562062(CHEMBL4754186)
Affinity DataKi:  27nMAssay Description:Binding affinity to sigma1 receptor (unknown origin) assessed as inhibition constantMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/19/2023
Entry Details
PubMed
TargetSigma non-opioid intracellular receptor 1(Human)
Helmholtz-Zentrum Dresden-Rossendor

Curated by ChEMBL
LigandPNGBDBM50562062(CHEMBL4754186)
Affinity DataKi:  27nMAssay Description:Displacement of [3H](+)-pentazocine from human sigma 1 receptor expressed in human HEK293 cells incubated for 2 hrs by liquid scintillation counting ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/18/2024
Entry Details
PubMed
TargetSigma intracellular receptor 2(Rat)
Helmholtz-Zentrum Dresden-Rossendor

Curated by ChEMBL
LigandPNGBDBM50562062(CHEMBL4754186)
Affinity DataKi:  750nMAssay Description:Displacement of (+)-[3H]DTG from sigma 2 receptor in SPRD rat liver membrane incubated for 2 hrs by liquid scintillation counting methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/28/2022
Entry Details Article
PubMed