BDBM50562049 CHEMBL4776765

SMILES O=c1ccoc2ccc(OCCCCN3CCCCC3)cc12

InChI Key InChIKey=YCJCZVUHPAFTTR-UHFFFAOYSA-N

Data  2 KI  7 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 9 hits for monomerid = 50562049   

TargetAcetylcholinesterase(Human)
Helmholtz-Zentrum Dresden-Rossendor

Curated by ChEMBL
LigandPNGBDBM50562049(CHEMBL4776765)
Affinity DataIC50: 5.58E+3nMAssay Description:Inhibition of human AChEMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/28/2022
Entry Details Article
PubMed
TargetCholinesterase(Human)
Helmholtz-Zentrum Dresden-Rossendor

Curated by ChEMBL
LigandPNGBDBM50562049(CHEMBL4776765)
Affinity DataIC50: 8.75E+4nMAssay Description:Inhibition of human BuChEMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/28/2022
Entry Details Article
PubMed
TargetAmine oxidase [flavin-containing] B(Human)
Helmholtz-Zentrum Dresden-Rossendor

Curated by ChEMBL
LigandPNGBDBM50562049(CHEMBL4776765)
Affinity DataIC50: 7.20E+3nMAssay Description:Inhibition of human MAO-BMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/28/2022
Entry Details Article
PubMed
TargetAcetylcholinesterase(Human)
Helmholtz-Zentrum Dresden-Rossendor

Curated by ChEMBL
LigandPNGBDBM50562049(CHEMBL4776765)
Affinity DataIC50: 5.58E+3nMAssay Description:Inhibition of human erythrocyte AChE using acetylthiocholine as substrate incubated for 3 mins by spectrophotometryMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/19/2023
Entry Details
PubMed
TargetAmine oxidase [flavin-containing] B(Human)
Helmholtz-Zentrum Dresden-Rossendor

Curated by ChEMBL
LigandPNGBDBM50562049(CHEMBL4776765)
Affinity DataIC50: 7.20E+3nMAssay Description:Inhibition of recombinant human MAO-B using p-tyramine as substrate preincubated for 30 mins followed by substrate addition measured for 60 mins by A...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/19/2023
Entry Details
PubMed
TargetAcetylcholinesterase(Human)
Helmholtz-Zentrum Dresden-Rossendor

Curated by ChEMBL
LigandPNGBDBM50562049(CHEMBL4776765)
Affinity DataIC50: 5.58E+3nMAssay Description:Inhibition of recombinant human AChE using acetylthiocholine as substrate measured after 3 mins by DTNB reagent based UV/Vis spectroscopyMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/18/2024
Entry Details
PubMed
TargetAmine oxidase [flavin-containing] B(Human)
Helmholtz-Zentrum Dresden-Rossendor

Curated by ChEMBL
LigandPNGBDBM50562049(CHEMBL4776765)
Affinity DataIC50: 7.20E+3nMAssay Description:Inhibition of recombinant human MAO-B expressed in baculovirus-infected insect cells using p-tyramine as substrate preincubated for 30 mins followed ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/18/2024
Entry Details
PubMed
TargetSigma non-opioid intracellular receptor 1(Human)
Helmholtz-Zentrum Dresden-Rossendor

Curated by ChEMBL
LigandPNGBDBM50562049(CHEMBL4776765)
Affinity DataKi:  309nMAssay Description:Displacement of [3H]pentazocine from human sigma 1 receptor expressed in HEK293 cell membrane incubated for 2 hrs by liquid scintillation counting me...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/28/2022
Entry Details Article
PubMed
TargetSigma intracellular receptor 2(Rat)
Helmholtz-Zentrum Dresden-Rossendor

Curated by ChEMBL
LigandPNGBDBM50562049(CHEMBL4776765)
Affinity DataKi:  1.97E+3nMAssay Description:Displacement of (+)-[3H]DTG from sigma 2 receptor in SPRD rat liver membrane incubated for 2 hrs by liquid scintillation counting methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/28/2022
Entry Details Article
PubMed