BDBM50562022 CHEMBL4797515

SMILES CNc1nc(C)c(s1)C(=O)\C=C\c1ccsc1

InChI Key InChIKey=PFXMWFGUBAGIJP-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50562022   

TargetTyrosine-protein kinase JAK2(Human)
University Bangkok

Curated by ChEMBL
LigandPNGBDBM50562022(CHEMBL4797515)
Affinity DataIC50: 18nMAssay Description:Inhibition of recombinant human JAK2 JH1 domain expressed in baculovirus infected insect cells using poly-Glu-Tyr (51 to 68 residues) as substrate in...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/28/2022
Entry Details Article
PubMed
TargetEpidermal growth factor receptor(Human)
University Bangkok

Curated by ChEMBL
LigandPNGBDBM50562022(CHEMBL4797515)
Affinity DataIC50: 144nMAssay Description:Inhibition of human EGFR TK domain expressed in Escherichia coli BL21 (DE3) pLysS using poly-Glu-Tyr (51 to 68 residues) as substrate incubated for 1...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/28/2022
Entry Details Article
PubMed