BDBM50561956 CHEMBL4764420

SMILES COc1ccc(cc1)C(=O)N[C@H]1CO[C@H](CCc2ccnc3ccc(OC)cc23)OC1

InChI Key InChIKey=LCTGAXAPOCTBBZ-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50561956   

TargetDNA gyrase subunit A/B(Staphylococcus aureus)
The Ohio State University

Curated by ChEMBL
LigandPNGBDBM50561956(CHEMBL4764420)
Affinity DataIC50: 3.90E+3nMAssay Description:Inhibition of Staphylococcus aureus DNA gyrase using relaxed pBR322 as substrate by gel electrophoresisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/28/2022
Entry Details Article
PubMed
TargetDNA topoisomerase 4 subunit A/B(Staphylococcus aureus)
The Ohio State University

Curated by ChEMBL
LigandPNGBDBM50561956(CHEMBL4764420)
Affinity DataIC50: 1.06E+5nMAssay Description:Inhibition of Staphylococcus aureus topoisomerase-4 assessed as reduction in decatenation of kinetoplast DNA agarose gel electrophoresis methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/28/2022
Entry Details Article
PubMed