BDBM50561928 CHEMBL4779888

SMILES Cc1cc(NC(=O)c2ccc(NS(=O)(=O)CCO)cc2N2CCC3(CC3)CC2)nc(n1)C1CCC(F)(F)CC1

InChI Key InChIKey=PRRASGDTJZCMFH-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50561928   

TargetKinesin-like protein KIF18A(Human)
Smith, Gambrell & Russell

Curated by ChEMBL
LigandPNGBDBM50561928(CHEMBL4779888)
Affinity DataIC50: 17nMAssay Description:Inhibition of recombinant human His-tagged KIF18A (1 to 467 residues) expressed in baculovirus expression system assessed as inhibition of microtubul...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/28/2022
Entry Details Article
PubMed