BDBM50561902 CHEMBL4757712

SMILES OB1OCc2ccc(NC(=S)NCc3ccccc3)cc12

InChI Key InChIKey=SWJMIANHGCEZLP-UHFFFAOYSA-N

Data  5 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50561902   

TargetCarbonic anhydrase 12(Human)
University of Montpellier

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50561902BDBM50561902(CHEMBL4757712)
Affinity DataKi:  42nMAssay Description:Inhibition of human carbonic anhydrase XII catalytic domain assessed as inhibition constant incubated for 15 to 360 mins by stopped-flow CO2 hydratio...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/6/2026
Entry Details
PubMed
TargetCarbonic anhydrase 1(Human)
University of Montpellier

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50561902BDBM50561902(CHEMBL4757712)
Affinity DataKi:  380nMAssay Description:Inhibition of human carbonic anhydrase I assessed as inhibition constant incubated for 15 to 360 mins by stopped-flow CO2 hydration assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/6/2026
Entry Details
PubMed
TargetCarbonic anhydrase 9(Human)
University of Montpellier

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50561902BDBM50561902(CHEMBL4757712)
Affinity DataKi:  610nMAssay Description:Inhibition of human carbonic anhydrase IX catalytic domain assessed as inhibition constant incubated for 15 to 360 mins by stopped-flow CO2 hydration...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/6/2026
Entry Details
PubMed
TargetCarbonic anhydrase 2(Human)
University of Florence

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50561902BDBM50561902(CHEMBL4757712)
Affinity DataKi:  1.31E+3nMAssay Description:Inhibition of human carbonic anhydrase 2 incubated for 30 mins prior to testing measured for 10 to 100 secs by phenol red-based stopped-flow CO2 hydr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/28/2022
Entry Details Article
PubMed
TargetCarbonic anhydrase 2(Human)
University of Florence

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50561902BDBM50561902(CHEMBL4757712)
Affinity DataKi:  1.31E+3nMAssay Description:Inhibition of human carbonic anhydrase II assessed as inhibition constant incubated for 15 to 360 mins by stopped-flow CO2 hydration assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/6/2026
Entry Details
PubMed