BDBM50561585 CHEMBL4788047

SMILES CCCC(=S)NCCCC[C@H](NC(=O)OCc1ccccc1)C(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(=O)NC(C)C

InChI Key InChIKey=QNYLBGIGZAKKCR-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50561585   

TargetNAD-dependent protein deacetylase sirtuin-1(Human)
University of Copenhagen

Curated by ChEMBL
LigandPNGBDBM50561585(CHEMBL4788047)
Affinity DataIC50: 540nMAssay Description:Inhibition of human recombinant N-terminal GST-tagged SIRT1 (193 to 741 residues) expressed in Escherichia coli using Ac-Gln-Pro-Lys-Lys(Ac)-AMC (oxo...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/28/2022
Entry Details Article
PubMed
TargetNAD-dependent protein deacetylase sirtuin-2(Human)
University of Copenhagen

Curated by ChEMBL
LigandPNGBDBM50561585(CHEMBL4788047)
Affinity DataIC50: 440nMAssay Description:Inhibition of human C-terminal His-tagged SIRT2 (50 to 356 residues) expressed in Escherichia coli using Ac-Gln-Pro-Lys-Lys(pro)-AMC (oxo-11) as subs...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/28/2022
Entry Details Article
PubMed