BDBM50561293 CHEMBL4785948

SMILES [H][C@@]12CC[C@@](O)(c3cn(nn3)-c3ccccc3)[C@@]1(C)CC[C@]1([H])c3ccc(O)cc3CC[C@@]21[H]

InChI Key InChIKey=YBJGVFATVAILGR-UHFFFAOYSA-N

Data  5 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50561293   

TargetEstrogen receptor beta(Human)
Marquette University

Curated by ChEMBL
LigandPNGBDBM50561293(CHEMBL4785948)
Affinity DataEC50:  6nMAssay Description:Displacement of fluormone from GST-tagged ERbeta receptor LBD (unknown origin) measured after 60 mins by TR-FRET competitive binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/28/2022
Entry Details Article
PubMed
TargetEstrogen receptor(Human)
Marquette University

Curated by ChEMBL
LigandPNGBDBM50561293(CHEMBL4785948)
Affinity DataEC50:  5nMAssay Description:Agonist activity at full length human ERalpha receptor assessed as transcriptional activity incubated for 22 to 24 hrs by cell based luciferase repor...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/28/2022
Entry Details Article
PubMed
TargetEstrogen receptor(Human)
Marquette University

Curated by ChEMBL
LigandPNGBDBM50561293(CHEMBL4785948)
Affinity DataEC50: >1.00E+3nMAssay Description:Antagonist activity at full length human ERalpha receptor assessed as inhibition of estradiol-induced activation incubated for 22 to 24 hrs by cell b...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/28/2022
Entry Details Article
PubMed
TargetEstrogen receptor beta(Human)
Marquette University

Curated by ChEMBL
LigandPNGBDBM50561293(CHEMBL4785948)
Affinity DataEC50: >1.00E+4nMAssay Description:Antagonist activity at full length human ERbeta receptor assessed as inhibition of estradiol-induced activation incubated for 22 to 24 hrs by cell ba...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/28/2022
Entry Details Article
PubMed
TargetEstrogen receptor beta(Human)
Marquette University

Curated by ChEMBL
LigandPNGBDBM50561293(CHEMBL4785948)
Affinity DataEC50:  2.10nMAssay Description:Agonist activity at full length human ERbeta receptor assessed as transcriptional activity incubated for 22 to 24 hrs by cell based luciferase report...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/28/2022
Entry Details Article
PubMed