BDBM50561195 CHEMBL4743401

SMILES NCc1cc(ccc1Cl)-c1cccc(c1)C(=O)Nc1ccccc1CC(O)=O

InChI Key InChIKey=ZFAJPOLKQKSTMN-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50561195   

TargetSuccinate receptor 1(Human)
Novartis Institutes For Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50561195(CHEMBL4743401)
Affinity DataIC50: 300nMAssay Description:Antagonist activity at human SUCNR1 expressed in human CHEM1 cells incubated for 60 mins in presence of [35S]GTPgammaS by scintillation proximity ass...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/28/2022
Entry Details Article
PubMed
TargetComplement factor D(Human)
Novartis Institutes For Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50561195(CHEMBL4743401)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of recombinant human CFD expressed in Escherichia coli incubated up to 2 hrs by TR-FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/28/2022
Entry Details Article
PubMed
TargetCoagulation factor XI(Human)
Novartis Institutes For Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50561195(CHEMBL4743401)
Affinity DataIC50: 5.80E+3nMAssay Description:Inhibition of human factor 11a by TR-FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/28/2022
Entry Details Article
PubMed