BDBM50561044 CHEMBL4743587::US11420984, Example 20

SMILES CC(C)(O)[C@H](N)C(=O)N[C@H]1CN[C@](CCCCB(O)O)(C1)C(O)=O

InChI Key InChIKey=LEJCPQUNZRIXOZ-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50561044   

TargetArginase-1(Human)
Oncoarendi Therapeutics

Curated by ChEMBL
LigandPNGBDBM50561044(CHEMBL4743587 | US11420984, Example 20)
Affinity DataIC50: 340nMAssay Description:Inhibition of human Arg1 by TOGA assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/28/2022
Entry Details Article
PubMed
TargetArginase-2, mitochondrial(Human)
Oncoarendi Therapeutics

Curated by ChEMBL
LigandPNGBDBM50561044(CHEMBL4743587 | US11420984, Example 20)
Affinity DataIC50: 520nMAssay Description:Inhibition of human Arg2 by TOGA assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/28/2022
Entry Details Article
PubMed
TargetArginase-1(Human)
Oncoarendi Therapeutics

Curated by ChEMBL
LigandPNGBDBM50561044(CHEMBL4743587 | US11420984, Example 20)
Affinity DataIC50: 340nMAssay Description:The inhibitory effects of Examples 1 to 30 on the activity of Human Arginase 1 and Arginase 2 activity were quantified by measuring the formation of ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/6/2022
Entry Details
Go to US Patent

TargetArginase-2, mitochondrial(Human)
Oncoarendi Therapeutics

Curated by ChEMBL
LigandPNGBDBM50561044(CHEMBL4743587 | US11420984, Example 20)
Affinity DataIC50: 520nMAssay Description:The inhibitory effects of Examples 1 to 30 on the activity of Human Arginase 1 and Arginase 2 activity were quantified by measuring the formation of ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/6/2022
Entry Details
Go to US Patent