BDBM50561034 CHEMBL4244287

SMILES N[C@@H](CSCCB(O)O)C(O)=O

InChI Key InChIKey=OTJHLDXXJHAZTN-UHFFFAOYSA-N

Data  2 KI  5 IC50  1 Kd

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 8 hits for monomerid = 50561034   

TargetArginase-1(Rat)
Oncoarendi Therapeutics

Curated by ChEMBL
LigandPNGBDBM50561034(CHEMBL4244287)
Affinity DataIC50: 5.00E+3nMAssay Description:Inhibition of rat Arg1 at pH 7.4More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/28/2022
Entry Details Article
PubMed
TargetArginase-1(Human)
Oncoarendi Therapeutics

Curated by ChEMBL
LigandPNGBDBM50561034(CHEMBL4244287)
Affinity DataKd:  270nMAssay Description:Binding affinity to human Arg1 at pH 8.5More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/28/2022
Entry Details Article
PubMed
TargetArginase-1(Rat)
Oncoarendi Therapeutics

Curated by ChEMBL
LigandPNGBDBM50561034(CHEMBL4244287)
Affinity DataIC50: 5.00E+3nMAssay Description:Inhibition of rat liver arginase using L-arginine as substrate incubated for 10 mins followed by substrate addition by scintillation counting analysi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/19/2024
Entry Details
PubMed
TargetArginase-1(Rat)
Oncoarendi Therapeutics

Curated by ChEMBL
LigandPNGBDBM50561034(CHEMBL4244287)
Affinity DataIC50: 5.00E+3nMAssay Description:Inhibition of rat ARG1More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/21/2024
Entry Details
PubMed
TargetArginase-1(Human)
Oncoarendi Therapeutics

Curated by ChEMBL
LigandPNGBDBM50561034(CHEMBL4244287)
Affinity DataIC50: 270nMAssay Description:Binding affinity to human ARG1 assessed as dissociation constantMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/21/2024
Entry Details
PubMed
TargetArginase-2, mitochondrial(Human)
Zhejiang University

Curated by ChEMBL
LigandPNGBDBM50561034(CHEMBL4244287)
Affinity DataIC50: 30nMAssay Description:Binding affinity to human ARG2 assessed as inhibition constantMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/21/2024
Entry Details
PubMed
TargetArginase-2, mitochondrial(Human)
Zhejiang University

Curated by ChEMBL
LigandPNGBDBM50561034(CHEMBL4244287)
Affinity DataKi:  30nMAssay Description:Inhibition of human Arg2 at pH 7.5More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/28/2022
Entry Details Article
PubMed
TargetArginase-2, mitochondrial(Human)
Zhejiang University

Curated by ChEMBL
LigandPNGBDBM50561034(CHEMBL4244287)
Affinity DataKi:  310nMAssay Description:Competitive inhibition of human ARG2More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/23/2024
Entry Details
PubMed