BDBM50560998 CHEMBL4759496

SMILES COc1ccc(cc1)S(=O)(=O)[N-]C(=O)c1cc2c(Nc3cccc(OC)c3)ccc(Cl)c2n1C

InChI Key InChIKey=SQXASPKIWQWIRR-UHFFFAOYSA-M

Data  2 IC50  2 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50560998   

TargetFructose-1,6-bisphosphatase 1(Human)
Peking Union Medical College

Curated by ChEMBL
LigandPNGBDBM50560998(CHEMBL4759496)
Affinity DataIC50: 29nMAssay Description:Inhibition of human liver FBPase expressed in Escherichia coli BL21(DE3) using FBP as substrate in presence of PGI and G6PDH by spectrophotometric me...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/28/2022
Entry Details Article
PubMed
TargetAdenosine kinase(Human)
Peking Union Medical College

Curated by ChEMBL
LigandPNGBDBM50560998(CHEMBL4759496)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of recombinant human ADK measured at interval of 1 to 2 mins for 30 to 40 mins by spectrophotometric methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/28/2022
Entry Details Article
PubMed
TargetGlycogen phosphorylase, liver form(Mouse)
Peking Union Medical College

Curated by ChEMBL
LigandPNGBDBM50560998(CHEMBL4759496)
Affinity DataEC50: >1.00E+5nMAssay Description:Activation of mouse liver Glycogen phosphorylaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/28/2022
Entry Details Article
PubMed
TargetATP-dependent 6-phosphofructokinase, liver type(Rat)
Peking Union Medical College

Curated by ChEMBL
LigandPNGBDBM50560998(CHEMBL4759496)
Affinity DataEC50: >1.00E+5nMAssay Description:Activation of rat liver phosphofructokinaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/28/2022
Entry Details Article
PubMed