BDBM50560871 CHEMBL4746307

SMILES NC1CN(C1)c1c(F)cc2c(c1Cl)n(cc(C(O)=O)c2=O)-c1nc(N)c(F)cc1F

InChI Key InChIKey=ZHLAKLNFEZYKHL-UHFFFAOYSA-N

Data  5 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50560871   

TargetCytochrome P450 1A2(Human)
Concept Life Sciences

Curated by ChEMBL
LigandPNGBDBM50560871(CHEMBL4746307)
Affinity DataIC50: 5.00E+4nMAssay Description:Inhibition of CYP1A2 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/28/2022
Entry Details Article
PubMed
TargetCytochrome P450 2C19(Human)
Concept Life Sciences

Curated by ChEMBL
LigandPNGBDBM50560871(CHEMBL4746307)
Affinity DataIC50: 5.00E+4nMAssay Description:Inhibition of CYP2C19 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/28/2022
Entry Details Article
PubMed
TargetCytochrome P450 2C9(Human)
Concept Life Sciences

Curated by ChEMBL
LigandPNGBDBM50560871(CHEMBL4746307)
Affinity DataIC50: 1.27E+4nMAssay Description:Inhibition of CYP2C9 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/28/2022
Entry Details Article
PubMed
TargetCytochrome P450 2D6(Human)
Concept Life Sciences

Curated by ChEMBL
LigandPNGBDBM50560871(CHEMBL4746307)
Affinity DataIC50: 5.00E+4nMAssay Description:Inhibition of CYP2D6 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/28/2022
Entry Details Article
PubMed
TargetCytochrome P450 3A4(Human)
Concept Life Sciences

Curated by ChEMBL
LigandPNGBDBM50560871(CHEMBL4746307)
Affinity DataIC50: 1.36E+4nMAssay Description:Inhibition of CYP3A4 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/28/2022
Entry Details Article
PubMed