BDBM50560684 CHEMBL4788725

SMILES CCc1nc2ccccc2n1-c1nc(N2CCOCC2)c2sc(CN3CCN(CC=C)CC3=O)cc2n1

InChI Key InChIKey=BVRGIASICSCQCP-UHFFFAOYSA-N

Data  4 IC50

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50560684   

TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform(Human)
Southwest Jiaotong University

Curated by ChEMBL

LigandBDBM50560684(CHEMBL4788725)Copy SMILESCopy InChI

Affinity DataIC50: 1.60nMAssay Description:Inhibition of PI3Kdelta (unknown origin)More data for this Ligand-Target Pair

Target InfoPDBKEGG
UniProtKB/SwissProt
GoogleScholar

Ligand InfoPC cidPC sidSimilars

In Depth
Date in BDB:
3/28/2022
Entry Details Article
Copy Entry DOIPubMed
Copy Rxn URL

TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform(Human)
Southwest Jiaotong University

Curated by ChEMBL

LigandBDBM50560684(CHEMBL4788725)Copy SMILESCopy InChI

Affinity DataIC50: 295nMAssay Description:Inhibition of PI3Kalpha (unknown origin)More data for this Ligand-Target Pair

Target InfoPDBKEGG
UniProtKB/SwissProt
GoogleScholar

Ligand InfoPC cidPC sidSimilars

In Depth
Date in BDB:
3/28/2022
Entry Details Article
Copy Entry DOIPubMed
Copy Rxn URL

TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit beta isoform(Human)
Southwest Jiaotong University

Curated by ChEMBL

LigandBDBM50560684(CHEMBL4788725)Copy SMILESCopy InChI

Affinity DataIC50: 232nMAssay Description:Inhibition of PI3Kbeta (unknown origin)More data for this Ligand-Target Pair

Target InfoPDBKEGG
UniProtKB/SwissProt
GoogleScholar

Ligand InfoPC cidPC sidSimilars

In Depth
Date in BDB:
3/28/2022
Entry Details Article
Copy Entry DOIPubMed
Copy Rxn URL

TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform(Human)
Southwest Jiaotong University

Curated by ChEMBL

LigandBDBM50560684(CHEMBL4788725)Copy SMILESCopy InChI

Affinity DataIC50: 266nMAssay Description:Inhibition of PI3Kgamma (unknown origin)More data for this Ligand-Target Pair

Target InfoPDBKEGG
UniProtKB/SwissProt
GoogleScholar

Ligand InfoPC cidPC sidSimilars

In Depth
Date in BDB:
3/28/2022
Entry Details Article
Copy Entry DOIPubMed
Copy Rxn URL