BDBM50560580 CHEMBL4759513

SMILES OC1(Cn2cnc3n(ncc3c2=O)-c2ccc(F)cc2)CCN(CC1)C(=O)C[C@@H](C(F)F)n1ccc(F)n1

InChI Key InChIKey=BLSNYSFLZAWBIV-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50560580   

TargetUbiquitin carboxyl-terminal hydrolase 7(Human)
Medivir

Curated by ChEMBL
LigandPNGBDBM50560580(CHEMBL4759513)
Affinity DataIC50: 52nMAssay Description:Inhibition of recombinant human His-tagged USP7 (208 to 560 residues) expressed in Hi-five Sf9 cells using monoubiquitinated ubiquitin-rhodamine as s...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/28/2022
Entry Details Article
PubMed
TargetUbiquitin carboxyl-terminal hydrolase 7(Human)
Medivir

Curated by ChEMBL
LigandPNGBDBM50560580(CHEMBL4759513)
Affinity DataIC50: 52nMAssay Description:Inhibition of human USP7 using Ub-Rho as substrateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/19/2024
Entry Details
PubMed
TargetUbiquitin carboxyl-terminal hydrolase 7(Human)
Medivir

Curated by ChEMBL
LigandPNGBDBM50560580(CHEMBL4759513)
Affinity DataIC50: 69nMAssay Description:Inhibition of human full length his tagged USP7 (208 to 560 residues) expressed in insect sf9 cells using monoubiquitinated ubiquitin-rhodamine as su...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/19/2024
Entry Details
PubMed
TargetUbiquitin carboxyl-terminal hydrolase 7(Human)
Medivir

Curated by ChEMBL
LigandPNGBDBM50560580(CHEMBL4759513)
Affinity DataIC50: 69nMAssay Description:Inhibition of human his tagged USP7 (208 to 560 residues) catalytic domain expressed in insect sf9 cells using monoubiquitinated ubiquitin-rhodamine ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/19/2024
Entry Details
PubMed