BDBM50560358 CHEMBL4790219

SMILES Cc1cc(cnc1OCC12CCC(N)(CC1)CC2)-c1nn(C)c2nc(N)ncc12

InChI Key InChIKey=ZGZDPGSCHBPJMQ-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50560358   

TargetToll-like receptor 7(Human)
Genomics Institute of The Novartis Research Foundation

Curated by ChEMBL
LigandPNGBDBM50560358(CHEMBL4790219)
Affinity DataIC50: 1nMAssay Description:Antagonist activity at TLR7 in human PBMC assessed as inhibition of ssRNA40-induced IFNalpha productionMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/28/2022
Entry Details Article
PubMed
TargetToll-like receptor 8(Human)
Genomics Institute of The Novartis Research Foundation

Curated by ChEMBL
LigandPNGBDBM50560358(CHEMBL4790219)
Affinity DataIC50: 1nMAssay Description:Antagonist activity at TLR8 in human THP-1 cells assessed as inhibition of resiquimod-induced TNFalpha productionMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/28/2022
Entry Details Article
PubMed
TargetToll-like receptor 9(Human)
Genomics Institute of The Novartis Research Foundation

Curated by ChEMBL
LigandPNGBDBM50560358(CHEMBL4790219)
Affinity DataIC50: 3.30E+3nMAssay Description:Antagonist activity at TLR9 in human PBMC assessed as inhibition of ODN2216-induced IFNalpha productionMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/28/2022
Entry Details Article
PubMed