BDBM50560210 CHEMBL4757922

SMILES COc1cc2OC(C)(CC(=O)NCCCCCCCCCNc3c4CCCCc4nc4ccccc34)CCc2cc1O

InChI Key InChIKey=DFXFXZRLHHKPPR-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50560210   

TargetAcetylcholinesterase(Human)
University of Barcelona (Ub)

Curated by ChEMBL
LigandPNGBDBM50560210(CHEMBL4757922)
Affinity DataIC50: 58nMAssay Description:Inhibition of recombinant human AChE expressed in HEK293 cells using acetylthiocholine iodide as substrate preincubated for 15 mins followed by subst...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/28/2022
Entry Details Article
PubMed
TargetCholinesterase(Human)
University of Barcelona (Ub)

Curated by ChEMBL
LigandPNGBDBM50560210(CHEMBL4757922)
Affinity DataIC50: 5.40nMAssay Description:Inhibition of recombinant human BChE using butyrylthiocholine iodide as substrate preincubated for 15 mins followed by substrate addition by Ellman's...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/28/2022
Entry Details Article
PubMed