BDBM50559939 CHEMBL4756373

SMILES CC(C)OP(=O)(OC(C)C)C(Cc1cc(nc(c1)C(C)(C)C)C(C)(C)C)P(=O)(OC(C)C)OC(C)C

InChI Key InChIKey=COEAYZDBKLLPNS-UHFFFAOYSA-N

Data  2 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50559939   

Target3-hydroxy-3-methylglutaryl-coenzyme A reductase(Human)
The University of Tokyo

Curated by ChEMBL
LigandPNGBDBM50559939(CHEMBL4756373)
Affinity DataEC50:  153nMAssay Description:Induction of degradation of Flag-tagged human HMGCR-dCat-ELuc membrane domain (1 to 499 residues) expressed in HEK293 cells assessed as reduction in ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/28/2022
Entry Details Article
PubMed
Target3-hydroxy-3-methylglutaryl-coenzyme A reductase(Human)
The University of Tokyo

Curated by ChEMBL
LigandPNGBDBM50559939(CHEMBL4756373)
Affinity DataEC50:  132nMAssay Description:Induction of HMGCR degradation in HEK293 cells incubated for 4 hrs by luciferase based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/20/2024
Entry Details
PubMed