BDBM50559792 CHEMBL4759458

SMILES COc1cc(NC(=O)c2ccccn2)ccc1NC(=O)c1ccc(NC(=O)COCC(=O)NCCCCCCCCCCNC(=O)COc2ccc(cc2C([O-])=O)-c2cccc(COc3cc4CC(C5CCCC5)C(=O)c4c(C)c3C)c2)cc1Cl

InChI Key InChIKey=YLKMRJVOFMUXFH-UHFFFAOYSA-M

Data  2 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50559792   

TargetMetabotropic glutamate receptor 2(Rat)
Vanderbilt University

Curated by ChEMBL
LigandPNGBDBM50559792(CHEMBL4759458)
Affinity DataEC50:  134nMAssay Description:Positive allosteric modulation of rat mGlu2 receptor expressed in HEK293 cells coexpressing GIRK assessed as thallium influx in presence of EC20 glut...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/28/2022
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 4(Rat)
Vanderbilt University

Curated by ChEMBL
LigandPNGBDBM50559792(CHEMBL4759458)
Affinity DataEC50: >1.00E+4nMAssay Description:Positive allosteric modulation of rat mGlu4 receptor expressed in HEK293 cells coexpressing GIRK assessed as thallium influx in presence of EC20 glut...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/28/2022
Entry Details Article
PubMed