BDBM50559762 CHEMBL4793958

SMILES COCCOc1cc2ncnc(Nc3ccc(\C=C\C(=O)NO)cc3)c2cc1OCCOC

InChI Key InChIKey=RGZPGGRAWSKJOG-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50559762   

TargetHistone deacetylase 1(Human)
Shandong First Medical University & Shandong Academy of Medical Sciences

Curated by ChEMBL
LigandPNGBDBM50559762(CHEMBL4793958)
Affinity DataIC50: 160nMAssay Description:Inhibition of recombinant human HDAC1 expressed in baculovirus expression system using Ac-Lys-Tyr-Lys (epsilon-acetyl)-AMC as substrate after 24 hrs ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/28/2022
Entry Details Article
PubMed
TargetHistone deacetylase 3(Human)
Shandong First Medical University & Shandong Academy of Medical Sciences

Curated by ChEMBL
LigandPNGBDBM50559762(CHEMBL4793958)
Affinity DataIC50: 180nMAssay Description:Inhibition of recombinant human HDAC3 expressed in baculovirus expression system using Ac-Lys-Tyr-Lys (epsilon-acetyl)-AMC as substrate after 24 hrs ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/28/2022
Entry Details Article
PubMed
TargetHistone deacetylase 6(Human)
Shandong First Medical University & Shandong Academy of Medical Sciences

Curated by ChEMBL
LigandPNGBDBM50559762(CHEMBL4793958)
Affinity DataIC50: 560nMAssay Description:Inhibition of recombinant human HDAC6 expressed in baculovirus expression system using Ac-Lys-Tyr-Lys (epsilon-acetyl)-AMC as substrate after 24 hrs ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/28/2022
Entry Details Article
PubMed
TargetHistone deacetylase 6(Human)
Shandong First Medical University & Shandong Academy of Medical Sciences

Curated by ChEMBL
LigandPNGBDBM50559762(CHEMBL4793958)
Affinity DataIC50: 2.77E+3nMAssay Description:Inhibition of recombinant human HDAC6 expressed in baculovirus infected Hi-5 insect cells using Boc-Lys (epsilon-acetyl)-AMC as substrate incubated f...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/20/2023
Entry Details
PubMed