BDBM50559706 CHEMBL4744560

SMILES COc1ccc(-c2nc(C(=O)NCc3coc4ccccc34)c(o2)[C@@H](C)N)c2ccc(nc12)C(F)(F)F

InChI Key InChIKey=KALDTHGTYJMUAA-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50559706   

TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4B(Human)
Sichuan Academy of Medical Science & Sichuan Provincial People'S Hospital

Curated by ChEMBL
LigandPNGBDBM50559706(CHEMBL4744560)
Affinity DataIC50: 0.0100nMAssay Description:Inhibition of recombinant human PDE4B2 using cAMP as substrate preincubated for 15 mins followed by substrate addition and measured after 60 mins by ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/28/2022
Entry Details Article
PubMed