BDBM50559646 CHEMBL4745494

SMILES COc1cccc(F)c1-c1cc2n(ncc2cn1)-c1cccc(n1)N1CCOCC1

InChI Key InChIKey=XPPHAMKKFBHWFX-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50559646   

TargetMitogen-activated protein kinase kinase kinase kinase 1(Human)
Schrodinger, Inc.

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50559646BDBM50559646(CHEMBL4745494)
Affinity DataIC50: 34nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/6/2026
Entry Details PubMed
TargetMitogen-activated protein kinase kinase kinase kinase 1(Human)
Schrodinger, Inc.

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50559646BDBM50559646(CHEMBL4745494)
Affinity DataIC50: 34nMAssay Description:Displacement of Tracer 222 from N-terminal GST-tagged human recombinant HPK1 (1 to 346 residues ) expressed in baculovirus-infected Sf9 cells incubat...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/28/2022
Entry Details Article
PubMed