BDBM50559514 CHEMBL4791596

SMILES COc1ccc(cc1O)-c1c2c(n3ccc4cc(O)c(OC)cc4c13)c(=O)[nH]c1cc(OCCCN(C)C)c(OCCCN(C)C)cc21

InChI Key InChIKey=UYSMPOTUUGPRIT-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50559514   

TargetEpidermal growth factor receptor(Human)
Nagasaki University

Curated by ChEMBL
LigandPNGBDBM50559514(CHEMBL4791596)
Affinity DataIC50: 4.60nMAssay Description:Inhibition of recombinant wild type EGFR (696 to C terminal end) (unknown origin) using poly (Glu-Tyr) as substrate preincubated for 30 mins followed...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/28/2022
Entry Details Article
PubMed
TargetEpidermal growth factor receptor(Human)
Nagasaki University

Curated by ChEMBL
LigandPNGBDBM50559514(CHEMBL4791596)
Affinity DataIC50: 1.70nMAssay Description:Inhibition of recombinant wild type EGFR T790M/L858R mutant (696 to C terminal end) (unknown origin) using poly (Glu-Tyr) as substrate preincubated f...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/28/2022
Entry Details Article
PubMed