BDBM50559479 CHEMBL4747052

SMILES CN1c2ccccc2C(=O)N(C)c2cnc(N[C@@H]3CC[C@H](O)CC3)cc12

InChI Key InChIKey=XDCQYSVFUPULSL-UHFFFAOYSA-N

Data  2 IC50  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50559479   

TargetBromodomain-containing protein 4(Human)
Kyorin Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50559479(CHEMBL4747052)
Affinity DataEC50:  3.07E+3nMAssay Description:Inhibition of BRD4 in human PBMC assessed as reduction in LPS-induced TNFalpha secretion preincubated for 1 hr followed by LPS-stimulation and measur...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/28/2022
Entry Details Article
PubMed
TargetMitogen-activated protein kinase 7(Human)
Kyorin Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50559479(CHEMBL4747052)
Affinity DataIC50: 2.23E+3nMAssay Description:Inhibition of recombinant human ERK5 using myelin basic protein as substrate by [gamm33P]ATP based HotSpot radiometric assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/28/2022
Entry Details Article
PubMed
TargetBromodomain-containing protein 4(Human)
Kyorin Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50559479(CHEMBL4747052)
Affinity DataIC50: 6.91E+3nMAssay Description:Inhibition of BRD4-BD1 (unknown origin) by TR-FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/28/2022
Entry Details Article
PubMed