BDBM50559468 CHEMBL4757477

SMILES CCOc1cc(ccc1Nc1cc2N(C)c3ccccc3C(=O)N(C)c2cn1)C(=O)N1CCC(CC1)N1CCCC1

InChI Key InChIKey=CBWCJYFVVHOTAZ-UHFFFAOYSA-N

Data  3 IC50  1 Kd

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50559468   

TargetBromodomain-containing protein 4(Human)
Kyorin Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50559468(CHEMBL4757477)
Affinity DataIC50: 1.29E+3nMAssay Description:Inhibition of BRD4-BD1 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/28/2022
Entry Details Article
PubMed
TargetBromodomain-containing protein 4(Human)
Kyorin Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50559468(CHEMBL4757477)
Affinity DataKd:  22nMAssay Description:Binding affinity to BRD4-BD1 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/28/2022
Entry Details Article
PubMed
TargetMitogen-activated protein kinase 7(Human)
Kyorin Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50559468(CHEMBL4757477)
Affinity DataIC50: 11nMAssay Description:Inhibition of ERK5 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/28/2022
Entry Details Article
PubMed
TargetPotassium voltage-gated channel subfamily H member 2(Human)
Kyorin Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50559468(CHEMBL4757477)
Affinity DataIC50: 320nMAssay Description:Inhibition of human ERGMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/28/2022
Entry Details Article
PubMed