BDBM50559435 CHEMBL4754584

SMILES CN1CC[C@@H](C1)NC(=O)c1cc(cs1)-n1cc(NC(=O)Nc2ccccc2Cl)cn1

InChI Key InChIKey=PSPGYOROKVJHTA-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50559435   

TargetMitogen-activated protein kinase 14(Human)
Reaction Biology

Curated by ChEMBL
LigandPNGBDBM50559435(CHEMBL4754584)
Affinity DataIC50: 2.00E+4nMAssay Description:Inhibition of P38alpha (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/27/2022
Entry Details Article
PubMed
TargetMitogen-activated protein kinase 9(Human)
Reaction Biology

Curated by ChEMBL
LigandPNGBDBM50559435(CHEMBL4754584)
Affinity DataIC50: 1.51E+3nMAssay Description:Inhibition of JNK2 (unknown origin) using ATF2 as substrate after 22 mins in presence of ATP by HTRF assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/27/2022
Entry Details Article
PubMed
TargetMitogen-activated protein kinase 8(Human)
Reaction Biology

Curated by ChEMBL
LigandPNGBDBM50559435(CHEMBL4754584)
Affinity DataIC50: 2.20E+3nMAssay Description:Inhibition of JNK1 (unknown origin) using ATF2 as substrate after 22 mins in presence of ATP by HTRF assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/27/2022
Entry Details Article
PubMed
TargetMitogen-activated protein kinase 10(Human)
Reaction Biology

Curated by ChEMBL
LigandPNGBDBM50559435(CHEMBL4754584)
Affinity DataIC50: 39nMAssay Description:Inhibition of JNK3alpha1 (unknown origin) using ATF2 as substrate after 22 mins in presence of ATP by HTRF assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/27/2022
Entry Details Article
PubMed