BDBM50559426 CHEMBL4753218

SMILES CN1CC[C@H](CNC(=O)c2cc(cs2)-n2cc(NC(=O)Nc3ccccc3Cl)cn2)C1

InChI Key InChIKey=ZILWEQNTUQYRDZ-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50559426   

TargetMitogen-activated protein kinase 14(Human)
Reaction Biology

Curated by ChEMBL
LigandPNGBDBM50559426(CHEMBL4753218)
Affinity DataIC50: 2.00E+4nMAssay Description:Inhibition of P38alpha (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/27/2022
Entry Details Article
PubMed
TargetMitogen-activated protein kinase 8(Human)
Reaction Biology

Curated by ChEMBL
LigandPNGBDBM50559426(CHEMBL4753218)
Affinity DataIC50: 1.03E+4nMAssay Description:Inhibition of JNK1 (unknown origin) using ATF2 as substrate after 22 mins in presence of ATP by HTRF assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/27/2022
Entry Details Article
PubMed
TargetMitogen-activated protein kinase 10(Human)
Reaction Biology

Curated by ChEMBL
LigandPNGBDBM50559426(CHEMBL4753218)
Affinity DataIC50: 222nMAssay Description:Inhibition of JNK3alpha1 (unknown origin) using ATF2 as substrate after 22 mins in presence of ATP by HTRF assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/27/2022
Entry Details Article
PubMed